RESUMEN El estudio se realizo con el fin de comparar el comportamiento térmico de los diferentes tipos de tejas mediante la medición de la temperatura de la superficie externa (EST) y La temperatura de La superficie interna (IST) durante el día. El diseño experimental fue completamente al azar, compuesto por 5 tratamientos:AC- Asbesto Cemento; BA-Bambú; BAP- Bambú Pintado de Blanco; FB- fibra vegetal y betún; FBP- fibra vegetal y betún pintado de Blanco, con 15 repeticiones, siendo considerados como repeticiones los días de medición. Fueron registradas las temperaturas de la superficie interior y de La superficie exterior de las tejas, a las 8:00am, 10:00am, 12:00pm, 2:00pm, 4:00pm y 6:00pm. Los datos fueron analizados por el programa SISVAR 5.1®, mediante el análisis de varianza y La prueba de Scott Knott para La comparación de medias, el nivel de significación del 1%.FB tuvo el peor desempeño térmico cuando se compara con las otras tejas, con mejor resultado para BAP.

ABSTRACT This study was developed in order to compare the thermal behavior of different types of roofs by measuring the External Surface Temperature (EST) and the Internal Surface Temperature (IST) over the days. The experimental design was completely randomized, with five treatments: AC - Asbestos cement tiles, BA -Bamboo tiles, BAP - Bamboo tiles painted in white, FB -Vegetable fiber tiles and bitumen, FBP -Vegetable fiber tiles and bitumen painted in white, with 15 repetitions, being adopted as repetitions the days of measurement. The temperature of the internal and external roofing surfaces was collected at 8:00am, 10:00am, 12:00pm, 2:00 pm, 4:00 pm and 6:00 pm. Data were analyzed by SISVAR 5.1® program through the analysis of variance and Skott Knott test for comparison of means, significance level at 1%. The FB coverage showed the worst thermal performance compared to other types of coverage, with the best results observed in BAP coverage.

The aim of this study was to determine the frequency of beta S-globin gene (βS globin) haplotypes and alpha thalassemia with 3.7 kb deletion (−α3.7kb thalassemia) in the northwest region of Paraná state, and to investigate the oxidative and clinical-hematological profile of βS globin carriers in this population. Of the 77 samples analyzed, 17 were Hb SS, 30 were Hb AS and 30 were Hb AA. The βSglobin haplotypes and −α3.7kb thalassemia were identified using polymerase chain reaction.Trolox equivalent antioxidant capacity (TEAC) and lipid peroxidation (LPO) were assessed spectophotometrically. Serum melatonin levels were determined using high-performance liquid chromatography coupled to coulometric electrochemical detection. The haplotype frequencies in the SS individuals were as follows: Bantu- 21 (62%), Benin - 11 (32%) and Atypical- 2 (6%). Bantu/Benin was the most frequent genotype. Of the 47 SS and AS individuals assessed, 17% (n = 8) had the −α3.7kb mutation. Clinical manifestations, as well as serum melatonin, TEAC and LPO levels did not differ between Bantu/Bantu and Bantu/Benin individuals (p > 0.05). Both genotypes were associated with high LPO and TEAC levels and decreased melatonin concentration. These data suggest that the level of oxidative stress in patients with Bantu/Bantu and Bantu/Benin genotypes may overload the antioxidant capacity.

This study was developed with the objective of evaluating reflective paint on covering and artificial ventilation on performance of broilers (males and females). A randomized design with a 2 × 2 × 2 factorial arrangement of treatments was used, as follows: 2 external management systems (coverage with and without reflective paint), 2 internal management systems (with and without artificial ventilation) and 2 sexes (male and female), totalizing 8 treatments. A total of 480 1-day old chicks of the Cobb strain were distributed randomly, according to sex, to treatments. Each treatment consisted of 4 pens - two pens for males and two for females - with 30 birds each. Six birds/pen were sampled. The studies were conducted at IFG-Urutaí Campus. For the performance evaluation, average weight, feed intake and mortality rate were measured weekly. There are differences between the performance of males and females, with males having greater weight gain and increased feed intake compared with females. The use of environmental changes, such as reflective paint or artificial ventilation, fosters weight gain and feed intake by broilers. There is positive effect of combined use of reflective paint and artificial ventilation in the feed intake of birds.

OBJECTIVE: The oxidative stress in 20 sickle cell anemia patients taking hydroxyurea and 13 sickle cell anemia patients who did not take hydroxyurea was compared with a control group of 96 individuals without any hemoglobinopathy. METHODS: Oxidative stress was assessed by thiobarbituric acid reactive species production, the Trolox-equivalent antioxidant capacity and plasma glutathione levels. RESULTS: Thiobarbituric acid reactive species values were higher in patients without specific medication, followed by patients taking hydroxyurea and the Control Group (p < 0.0001). The antioxidant capacity was higher in patients taking hydroxyurea and lower in the Control Group (p = 0.0002 for Trolox-equivalent antioxidant capacity and p < 0.0292 for plasma glutathione). Thiobarbituric acid reactive species levels were correlated with higher hemoglobin S levels (r = 0.55; p = 0.0040) and lower hemoglobin F concentrations(r = -0.52; p = 0.0067). On the other hand, plasma glutathione levels were negatively correlated with hemoglobin S levels (r = -0.49; p = 0.0111) and positively associated with hemoglobin F values (r = 0.56; p = 0.0031). CONCLUSION: Sickle cell anemia patients have high oxidative stress and, conversely, increased antioxidant activity. The increase in hemoglobin F levels provided by hydroxyurea and its antioxidant action may explain the reduction in lipid peroxidation and increased antioxidant defenses in these individuals.

Mexilhões são periodicamente submetidos a condições de hipóxia seguido de normóxia, como resultado das oscilações nos níveis de maré. Tais condições podem causar um aumento na produção de espécies reativas de oxigenio (EROs) nos tecidos, devido a um aumento no fluxo de oxigênio e de equivalentes redutores. Para proteger as células contra as EROs, os organismos possuem enzimas antioxidantes tais como a superóxido dismutase (SOD), catalase (CAT) e glutationa peroxidase (GPx), assim como o tripeptídeo glutationa (GSH). Neste trabalho, estas defesas antioxidantes foram avaliadas em glândulas digestivas de mexilhões Perna perna expostos ao ar por 4 horas seguido de re-submersão em água do mar por 30 minutos e constantemente submersos por 4,5 horas. Nenhuma diferença foi observada nas atividades da CAT e GPx, assim como nos níveis de GSH total. Mexilhões expostos ao ar tiveram atividade da SOD significativamente maior, possivelmente relacionado a um mecanismo de defesa preparativo contra o estresse oxidativo durante a reoxigenação.

Investigations were carried out to evaluate the antioxidant defenses in digestive gland of mussels Perna perna held in air for 4 hours, exposed to air for 4 hours followed by submersion in water for 30 minutes, and constantly submerged for 4.5 hours. No differences were observed in CAT and GPx activities and in the levels of total GSH. Mussels exposed to air had significantly higher SOD activity, possibly related to a preparative mechanism of defense against oxidative stress during reoxygenation.